Typical Presentations – Prescribed Medication

There are two typical presentations of a drug induced dystonic reaction:

  1. A young male recently started on, or with a rapid dose increase of, neuroleptics
  2. A patient in whom prophylactic medication to prevent acute extrapyramidal symptoms has been missed, stopped or reduced

Acute dystonia is commonly induced by anti-psychotics, anti-emetics or antidepressants but has been attributed less commonly to many other classes of drugs. (Evidence grade 2B).