Kawasaki disease is a clinical diagnosis but as many children have incomplete Kawasaki disease, some investigations, although nonspecific, are useful in supporting a diagnosis.
Investigation | Result | Comment |
FBC | WCC >15 Hb Mild to moderate anaemia Platelets >450 (peaks at 3rd week) | Kawasaki disease is an inflammatory process with elevation of WCC, CRP and ESR. The absence of significant inflammation makes the diagnosis of Kawasaki disease unlikely. |
CRP | Raised | |
ESR | >40 | |
LFTs | Albumin <30 ALT Elevated Bilirubin Raised in 10% | Hepatitis can develop with 40% of patients having raised aminotransferases |
Urinalysis | Sterile pyuria | Abnormal urinalysis should prompt culture of sample to exclude UTI |
Chest X-ray | Cardiomegaly or evidence of heart failure | |
ECG | Conduction abnormalities, myocardial ischaemia |