You have diagnosed severe lower leg cellulitis in an elderly, beta-blocked woman. Her observations are P 110, BP 90/42, RR 20, sats 100% on high-flow O2. She has a lactate of 3 after 1500 ml of carefully titrated fluids. You have started an IV penicillin via infusion. You are anticipating initiating early goal directed therapy when you note a sudden deterioration: P 120 sinus tachycardia, BP 50/-. You are able to palpate a femoral pulse and a note a developing urticarial rash.