July 2022 Journal Club – Summative Assessment

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Question 1 of 5

1. Question
Which of the following reporting criteria should be used for randomised clinical trials?
- STROBE
- CONSORT
- STARO
- GRADE
- QUDAS
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Question 2 of 5

2. Question
The following statement is true for confounding variables:
- Help reduce bias
- Help assess the margin of error
- Is associated with both the exposure and outcome of interest
- Does not affect the results
- Helps measure concordance
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Question 3 of 5

3. Question
With regards to the power of a study:
- Power refers to the number of patients required to avoid a type I error in a comparative study.
- The power of a study is independent of sample size.
- A power of 0.6 is generally considered sufficient for a study.
- A power of 0.8 means there is a 20 percent chance of detecting a predetermined difference in measurement between 2 groups, if a difference exists.
- A power of 0.8 means there is an 80 percent chance of detecting a predetermined difference in measurement between 2 groups, if a difference exists.
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Question 4 of 5

4. Question
With regards to hazard ratio:
- Hazard ratio is calculated as hazard in the control group/hazard in the intervention group.
- Hazard ratio and relative risk are interchangeable.
- the 95% confidence interval of the hazard ratio spans 1 this indicates that the hazard ratio is significant.
- This study reports an adjusted hazard ratio of 0.91; this indicates that at any particular time, 91% of patients in the early CT angiography group are experiencing the primary outcome (all cause death or non-fatal type 1/4b MI) compared to the control group.
- An assumption of proportional hazards regression is that the hazard ratio changes over time.
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Question 5 of 5

5. Question
CT coronary angiography has a high negative predictive value for coronary artery disease. Negative predictive value…
- Is the proportion of people with a negative test who don’t have the disease.
- Is the proportion of people with a negative test who do have the disease.
- Is the proportion of people with a positive test who don’t have the disease.
- Is independent of prevalence.
- Is unlikely to significantly change if there is a change in the population in which the test is performed.
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Virtual Journal Club – Early computed tomography coronary angiography for ACS

July 2022 Journal Club – Summative Assessment

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